2012-1-10

De Novo Sequencing Assisted Database Search for Sensitive and Accurate Peptide Identification

Waterloo, Ontario – Database searching is the most common form of protein and peptide identification and researchers prefer this approach as it is very fast and very familiar. But is it the best? The danger is when the decision for speed takes priority over accuracy. While a 0% FDR is highly unlikely for any automated process without removing some quality candidates, there is one method which ensures the lowest FDR while maintaining high sensitivity. The approach integrates de novo sequencing results into the database search.

In 2011, BSI participated in the following meetings and conferences:

ETP Atlantic
• Boston, MA, USA (October 7, 2011)

Congrès de spectrométrie de Masse Appliquée à la Protéomique (SMAP)
• Avignon, France (September 19 - 22, 2011)

Post ASMS Meetings
• Toronto, Ontario, Canada (September 21, 2011)
• Montreal, Quebec, Canada (September 22, 2011)
• Vancouver, British Columbia, Canada (September 29, 2011)

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